Tentative Lecture Schedule: Physical Biochemistry 2015


 Date  Topic  Reading
Fri Jan. 16 Introduction, Macromolecules, Interactions (1) Chapter 1
Wed Jan. 21 Structure of Proteins (2) Chapter 1
Fri Jan. 23 No Class  
Wed Jan. 28 Structure of Nucleic Acids (3) Chapter 1
Fri Jan. 30 Thermodynamics, Part I (4) Chapter 2
Wed Feb. 4 Thermodynamics, Part II (5) Chapter 2
Fri Feb. 6 Modeling Macromolecular  Structure (6) Chapter 3
Wed Feb. 11 Stabilizing Interactions in Macromolecules (7) Chapter 3
Fri Feb. 13 Exam I Chapters 1, 2
Wed Feb. 18

Modeling Nucleic Acids &

Intro to Statistical Mechanics (8)

Chapter 3
Fri Feb. 20

Structural Transitions in  Macromolecules (9)

Chapters 3, 4
Wed Feb. 25 Structural Transitions in  Nucleic Acids/Random Walks/Simple Exact Models(10) Chapter 4
Fri Feb 27 Diffusion and Introduction to Sedimentation (11) Chapter 5
Wed Mar 4 Interpreting the Sedimentation Coefficient/ Zonal Sedimentation (12) Chapter 5
Fri Mar. 6 Exam II Chapters 3, 4
Wed Mar. 11 Spring Break
Fri Mar. 13 Spring Break  
Wed Mar. 18 General Principles of Electrophoresis (13) Chapters 5
Fri Mar. 20 Electrophoresis continued & Solution Thermodynamics (14) Chapter 5, 13
Wed Mar. 25 Chemical Potential/Osmotic Pressure/ Sedimentation Equilibrium (15) Chapter 13
Fri Mar. 27 Chemical Equilibria Involving Macromolecules (16) Chapter 14
Wed Apr. 1 Binding of Small Ligands by Macromolecules (17) Chapter 14
Fri Apr. 3 Holiday-No class  
Wed Apr. 8 Exam III Chapter 5, 13
Fri Apr. 10 Cooperativity in Binding & Proton Binding(18) Chapter 14
Wed Apr. 15 Binding to Nucleic Acids, Viscosity, and Introduction to Mass Spectometry(19) Chapters 14, 15
Fri Apr. 17 Mass Spectrometry (20) Chapter 15
Wed Apr. 22 Fluorescence (21) Chapter 11
Fri Apr. 24

Single Molecule Analysis

Chapter 16
Wed Apr. 29 Exam IV Ch. 11, 14, 15,16
Fri May 1 Student Presentations  
Wed May 6 Papers due, 3:00 PM (Final exam date)  

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Last updated Saturday, January 3, 2015


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Copyright 2015, Steven B. Vik, Southern Methodist University