CURRICULUM VITAE
Steven B. Vik
Educational Training:
1975 California Institute of Technology, Pasadena, CA
B.S. (Chemistry)
1980 University of Oregon, Eugene, OR
Ph.D. (Chemistry - Biochemistry)
Positions Held:
1980-82 Research Associate, Department of Biochemistry, Scripps Clinic and Research Foundation, La Jolla, CA
1982-83 Visiting Research Scholar, Chinese Academy of Sciences, Institute of Zoology, Department of Cell Biology, Beijing, People's Republic of China
1983-87 Postdoctoral Research Fellow, Department of Biological Sciences, Stanford University, Stanford, CA
1987-1993 Assistant Professor, Department of Biological Sciences, Southern Methodist University, Dallas, TX
1993-1999 Associate Professor, Department of Biological Sciences, Southern Methodist University, Dallas, TX
1999-present Professor, Department of Biological Sciences, Southern Methodist University, Dallas, TX
2008-2010 Guangbiao Professor, Zhejiang University, Department of Tea Science, Hangzhou, China
2011-2014 Chair, Department of Biological Sciences, Southern Methodist University, Dallas, TX
Societies
American Association for the Advancement of Science
American Chemical Society
American Society for Microbiology
American Society for Biochemistry and Molecular Biology
Awards:
Postdoctoral Research Fellowship, American Heart Association, California Affiliate, 1981-1982.
Research Fellowship, National Program for Advanced Study and Research in China, Committee on Scholarly Communications with the People's Republic of China, 1982-1983.
Postdoctoral Research Fellowship, Program in Cancer Biology, Stanford University, 1983-1984.
Outstanding Research Award, Southern Methodist University Chapter of Sigma Xi, 1993.
Ford Research Fellowship, Southern Methodist University, 2008.
Dedman Family Distinguished Professor, Southern Methodist University, 2019.
Research Grants
National Institutes of Health Research Grant, RO1-40508, "Structure-Function Studies of the E. coli F1Fo ATPase," Southern Methodist University, 1988-2003.
National Institutes of Health Supplement to RO1-40508 to support a minority undergraduate (Douglas Patton), 1992-1994.
National Institutes of Health Supplement to RO1-40508 to support an undergraduate, Cindy Kluender (SURE program), 1993.
Welch Foundation, N-1378, "Metal Chelate Mediated Proteolysis of Membrane Proteins," Southern Methodist University, 1997-2000
Welch Foundation, N-1378, "Chemical Proteolysis and Cross-linking of Membrane Proteins," Southern Methodist University, 2000-2003
Welch Foundation, N-1378, "Interactions of Membrane Proteins," Southern Methodist University, 2003-2006
American Heart Association, 0455139Y, “Quinone Binding Sites in Complex I and their possible role in disease”, Southern Methodist University. 2004-2006
National Institutes of Health Research Grant, RO1-40508, "Structure-Function Studies of the E. coli F1Fo ATPase," Southern Methodist University, 2005-2009
Welch Foundation, N-1378, “Analysis of Supercomplexes of Membrane-bound Enzymes”, Southern Methodist University, 2006-2009
National Institutes of Health Research Grant, R15-099014, " Complex I: Role of L Subunit in Proton Translocation," Southern Methodist University, 2011-2015
American Heart Association, 17AIREA33661165, “Impact of Clinical Mutations on Assembly of the NADH-module of Complex I”, Southern Methodist University. 2017-2019
National Institutes of Health Research Grant, 1R15GM126507, "Impact of Clinical Mutations on Subunit Interactions in Complex I," Southern Methodist University, 2017-2020
Editorial Board
Journal of Biological Chemistry 2005-2010, 2012-2017
Recent Publications (My Bibliography at NCBI)
Dang QL, Phan DH, Johnson AN, Pasapuleti M, Alkhaldi HA, Zhang F, Vik SB. Analysis of Human Mutations in the Supernumerary Subunits of Complex I. Life (Basel). 2020 Nov 20;10(11). doi: 10.3390/life10110296. Review. PubMed PMID: 33233646; PubMed Central PMCID: PMC7699753.
Galkin, M.A., Russell, A.N., Vik, S.B., Berry, R.M., Ishmukhametov, R.R. Detergent-free Ultrafast Reconstitution of Membrane Proteins into Lipid Bilayers Using Fusogenic Complementary-charged Proteoliposomes.. J. Vis. Exp. (134), e56909, (2018). PMC
URL: https://www.jove.com/video/56909
Ishmukhametov, R.R., DeLeon-Rangel, J., Zhu, S., and Vik, S.B. (2017) Analysis of an N-terminal deletion in subunit a of the Escherichia coli ATP synthase. J. Bioenerget. Biomembr. 49:171-181. PMC
Tursun, A., Zhu, S., and Vik, S.B. (2016) Probing the proton channels in subunit N of Complex I from Escherichia coli through intra-subunit cross-linking. Biochim Biophys Acta. 1857, 1840-1848. PMC
Zhu, S., Canales, A., Bedair, M., and Vik, S.B. (2016) Loss of Complex I activity in the Escherichia coli enzyme results from truncating the C-terminus of subunit K, but not from cross-linking it to subunits N or L. J. Bioenerget. Biomembr. 48, 325-333. PMC
Zhu, S., and Vik, S.B. (2015) Constraining the Lateral Helix of Respiratory Complex I by Cross-linking Does Not Impair Enzyme Activity or Proton Translocation. J. Biol. Chem. 290, 20761-20773. PMC
DeLeon-Rangel, J., Ishmukhametov, R.R., Jiang, W., FIllingame, R.H., and Vik, S.B. (2013) Interactions between subunits a and b in the rotary ATP synthase as determined by cross-linking. FEBS Lett. 587, 892-897. PMC
Li, Bo,. Vik, S. B., Tu, Y. (2012) Theaflavins inhibit the ATP synthase and the respiratory chain without increasing superoxide production. J. Nutr. Biochem. 23, 953-960. PubMed