Conservation in nuoJ Back to subunit list
The membrane sector of E. coli Complex I is shown with each of the 6 subunits colored a different color. The peripheral arm and subunit H of the membrane arm are missing.

 nuoL  ND5  :L
 nuoM  ND4  :M
 nuoN  ND2  :N
 nuoK  ND4L  :K
 nuoJ  ND6  :J
 nuoA  ND3  :A
         
Subunit J is colored according to conservation. Magenta is most conserved, cyan is least conserved. Several lipids, detergents and internal water molecules are shown in space filling.

Isolated view of subunit J.

L36 in nuoJ     Undo   
V58 in nuoJ    Undo   
M72 in nuoJ    Undo   
L74 in nuoJ    Undo   
I111 in nuoJ    Undo   
V114 in nuoJ    Undo   
G118 in nuoJ    Undo

 
Atoms within 6 Å of subunit J are shown in cpk according to the coloring scheme:

 nuoN  ND2  :N
 nuoL  ND5  :l
 nuoK  ND4L  :K
 nuoA  ND3  :A
         
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Most conserved residues of subunit J .

Tyr 59, in the proton channel, colored lime.


Structure of the membrane domain of respiratory complex I.
Efremov RG, Sazanov LA.
Nature. 2011 Aug 7;476(7361):414-20.(PubMed)

pdb number (3rko)