Conservation in nuoK Back to subunit list
The membrane sector of E. coli Complex I is shown with each of the 6 subunits colored a different color. The peripheral arm and subunit H of the membrane arm are missing.

 nuoL  ND5  :L
 nuoM  ND4  :M
 nuoN  ND2  :N
 nuoK  ND4L  :K
 nuoJ  ND6  :J
 nuoA  ND3  :A
Subunit K is colored according to conservation. Magenta is most conserved, cyan is least conserved. Several lipids, detergents and internal water molecules are shown in space filling.

Isolated view of subunit K.

N27 in nuoK     Undo   
A43 in nuoK    Undo   
S67 in nuoK    Undo   
A73 in nuoK    Undo   

Atoms within 6 Å of subunit K are shown in cpk according to the coloring scheme:

 nuoN  ND2  :N
 nuoL  ND5  :l
 nuoJ  ND6  :J
 nuoA  ND3  :A
Spin on   Spin off
Protein wireframe   Protein cpk
Zoom 400   Zoom 600   Zoom 800

Most conserved residues of subunit K .

Glu 36 (and 72), in the proton channel, colored lime.

Structure of the membrane domain of respiratory complex I.
Efremov RG, Sazanov LA.
Nature. 2011 Aug 7;476(7361):414-20.(PubMed)

pdb number (3rko)