|Conservation in nuoM||Back to subunit list|
The membrane sector of E. coli Complex I is shown with each of the 6 subunits colored a different color. The peripheral arm and subunit H of the membrane arm are missing.
Subunit M is colored according to conservation. Magenta is most conserved, cyan is least conserved. Several lipids, detergents and internal water molecules are shown in space filling. Isolated view of subunit M.
L183 in nuoM (L158) UndoAtoms within 6 Å of subunit M are shown in cpk according to the coloring scheme:
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Protein wireframe Protein cpk
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Conserved residues of M. Glu 144, Lys 234,Lys 265, His 322, Glu 407, in the proton channel of nuoM, colored lime.
Efremov RG, Sazanov LA.
Structure of the membrane domain of respiratory complex I.
Nature. 2011 Aug 7;476(7361):414-20.PubMed)
pdb number (3rko)