1ag9 (PDB)
A flavodoxin that is required for enzyme activation: the structure of oxidized flavodoxin from Escherichia coli at 1.8 A resolution.
Hoover DM, Ludwig ML.
Protein Sci. 1997 Dec;6(12):2525-37.(PubMed)
| Flavodoxin: Open twisted sheet | |
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A 5-stranded parallel beta sheet runs through the center of the protein. The strands do not appear in order (See above). Strand 5 is interrupted by a long irregular segment.
The placement of the helices is according to the right-handed connectivity rule. Helix 1 (red) is on one side of the sheet, while helices 2-4 are on the other side. Helix 5 is on the first side. It can be anywhere since it does not connect to another beta strand. The two loops at the switch point are colored cyan.
The substrate, flavin mononucleotide, binds to the loops at the switch point. This is at the C-terminal ends of the beta strands.
1ag9 (PDB) A flavodoxin that is required for enzyme activation: the structure of oxidized flavodoxin from Escherichia coli at 1.8 A resolution. |