HincII endonuclease forms a short segment of PPII helix that binds in the minor groove of its target DNA

HincII is a dimeric enzyme. One subunit is colored light blue and one is colored magenta. The DNA segment is colored yellow. Each protein subunit forms a short segment of PPII helix, colored red in the light blue subunit, which lies in the minor groove of the DNA.


DNA distortion and specificity in a sequence-specific endonuclease.
Babic, A.C., Little, E.J., Manohar, V.M., Bitinaite, J., Horton, N.C.
(2008) J.Mol.Biol. 383: 186-204

(PubMed)

3e45 (PDB)