Spacefilling view with Valine, Isoleucine, and Leucine residues colored Magenta.

12.1. Find 3 residues whose side chains are nearly completely buried.

12.2. Now find 3 with side chains that are highly exposed.

12.3. What principle does this violate? How could you justify this violation if you knew that this protein interacted with several other proteins?

Next: Phenylalanine

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