Glyceroporin
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Glyceroporin is a tetramer. It has a central channel that might be active in some related proteins.
Cartoons view of one monomer of glyceroporin. One half is colored cyan and one half is colored violet. The homologous halves have an inverted orientation with respect to each other. The NPA sequences are in spacefilling. Notice the helices that meet in the middle. A narrow channel is visible. This allows glycerol molecules to travel in single file through the protein.Fu, D., Libson, A., Miercke, L. J. W., Weitzman, C., Nollert, P., Krucinski, J., Stroud, R. M.: Structure of a Glycerol Conducting Channel and the Basis for its Selectivity Science 290 pp. 481 (2000) 1fx8 (PDB) |