| Mouse PrP
There is a core of 2 long helices in a hairpin. Two short β-strands are antiparallel, and are connected by a short helix. This region seems to undergo conformational changes when the PrP aggregates, in its pathological form.
Riek, R., Hornemann, S., Wider, G., Billeter, M., Glockshuber, R., Wuthrich, K. 1ag2 (PDB) |