A dimeric human Prp is domain-swapped. Interestingly, this also requires disulfide swapping (cysteines in red).

Knaus KJ, Morillas M, Swietnicki W, Malone M, Surewicz WK, Yee VC.

Crystal structure of the human prion protein reveals a mechanism for oligomerization.
Nat Struct Biol. 2001 Sep;8(9):770-4.
(PubMed)

1i4m (PDB)