Peroxiredoxin 5

The sulfur atoms of Cys47 and Cys151 are positioned too far apart A large conformational changes must occur in PRDX5 upon oxidation.

Crystal structure of human peroxiredoxin 5, a novel type of mammalian peroxiredoxin at 1.5 A resolution. Declercq, J.P., Evrard, C., Clippe, A., Stricht, D.V., Knoops, A.Bernardb., (2001) J.Mol.Biol. 311: 751
(PubMed)

1HD2 (PDB)

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