hsG6PD (R459L) mutant variant monomer

hsG6PD displaying conserved important residues between lmG6PD; nine residue peptide in red- RIDHYLGKE, a nucleotide-binding fingerprint in blue- GxxGDLA, and a five residue coenzyme coordinating sequence in green- EKPxG

Au, S.W.N., Gover, S., Lam, V.M.S., Adams, M.J Human glucose-6-phosphate dehydrogenase: the crystal structure reveals a structural NADP(+) molecule and provides insights into enzyme deficiency. (2000) Structure 8: 293-303
(PubMed)

1QKI (PDB)

 

lmG6PD monomer

lmG6PD displaying conserved important residues between lmG6PD; nine residue peptide in red- RIDHYLGKE, a nucleotide-binding fingerprint in blue- GxxGDLA, and a five residue coenzyme coordinating sequence in green- EKPxG

Rowland, P., Basak, A.K., Gover, S., Levy, H.R., Adams, M.J., The three-dimensional structure of glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides refined at 2.0 Aresolution. (1994) Structure 2: 1073-1087(PubMed)

1DPG (PDB)

Table of Contents