This view shows five domains including MBP domain (in grey), two TMDs (in green and yellow) and two NBDs (in brown and red).
This view shows a detailed structure of the NBDs. View along an axis perpendicular to the membrane plane from the trans-side onto the NBDs. The TMDs and MBP were removed from better visualization. The A-loop (in red) contains tyrosine that helps to position the ANP (in blue);Walker A motif (a separate helix in yellow on the top right, which is RecA-like domain) directly interacts with the phosphates of ANP;The walker B motif (the second beta-stand in yellow on the left of RecA-like domain).It helps to coordinate the magnesium (second biggest spheres next to ATP) via the conserved aspartate residue. The top left and bottom right are alpha-helical domains (in yellow and grey).
This review shows a closer look of the NBD. ANP is shown in wireframe (in yellow) and sphere (in blue) at the same time.

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