This view shows the interaction between Helix HL.Helix HL stabilizes the complex. It is tightly anchored to NuoN, and K by L(TM16), which also contacts N(TM7). HL contacts NuoM; HL is unwound, allowing for strong interactions via the backbone and side chains..Helix HL forms hydrogen bonds to the main body of the domain near TM7 of NuoL and N. These contacts involve conserved M(Lys 173)*, M(Asp 246)* and M(Tyr 317)*, and a semiconserved residue, M(His 241); color green.

Structure of the membrane domain of respiratory complex I.

Efremov RG1, Sazanov LA

(PubMed)

3rko (PDB)