| Overall Structure of TIGAR |
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The Overall
Secondary Structure of TIGAR
The overall structure is composed of 9 alpha helices and 7 beta strands. Helices are colored corn flower blue and sheets are colored orange. Core Region of TIGARα/β/α sandwich forms the tryptic core fragment with six-stranded β sheet that is flanked by two helices on each side.β sheet are colored light blue and α helices are colored pale violet red. Active site is enclosed by three-helicesHelices α5, α6 and short helix α1 together function as a cap to enclose active site in core region. Two bound phosphate molecules are shown in spacefilling view. Helices are colored lavender.
Hua Li and Gerwald Jogl 3E9D (PDB) |