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Crosslinking sites and conserved residues in nuoN Back
Subunit N

TM4-8 lightblue, TM9-13 salmon.

% loss of activity shown
142-green, 238-yellow   
152-green, 234-yellow

293-green, 358-yellow   8% ?
343-green, 372-yellow 9%
377-blue, 429-red 31%

No cross-linking
128-green, 170-yellow
128-green, 253-yellow.
177-green, 203-yellow

311-cyan, 410-magenta 10-30% ?
315-blue, 401-red 33%
322-blue, 401-red 23%

301-blue, 383-red 50%?
305-blue, 383-red 40%

Glu 133
Lys 217
Lys 247
Lys 395
Lys 158
His 224
Tyr 300
Link to cytoplasm: 239,295,355,357, (156,160)
Main cavity: 217,136,163,167,246,159,133
Connection: 219,227,231,302, 333,337
Main cavity: 395,308,329,305,418, 382,336,304,285,301,425,424
Link to periplasm: 322


Structure of the membrane domain of respiratory complex I.
Efremov, R.G., Sazanov, L.A.
(2011) Nature 476: 414-420 (PubMed)

3rko(PDB)