Conservation in subunit FA13 Back to subunit list
Human Complex I is shown with each of the 45 subunits colored a different color. The prosthetic groups, including FMN, FeS clusters, quinone, NADP+ and lipids are shown in space filling, colored by cpk.

Subunit FA13 is colored according to conservation. Magenta is most conserved, cyan is least conserved.

Isolated view of subunit FA13 (chain W).

R57 (R23) in FA13    Undo
S83 (S49)in FA13    Undo
K88 (K54) in FA13    Undo
R198 in FA13 is not seen. Possibly fund in a longer isoform.   >
Atoms within 6 Å of subunit FS6 are shown in cpk according to the coloring scheme:
                       
 ND1  nuoH  :s
 ND3  nuoA  :j
 ND6  nuoJ  :m
 FS2  nuoD  :Q
 FS5      :h
 FS8  nuoI  :B
 FA1    :S
 FA3    :U
 FA7    :I
 FA8    :u
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Protein cartoon   Colored by sec. structure
Rainbow color: N-term-blue, C-term-red
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To show the atoms that contact residue 377 of NDUFV1 (:A),first select "color all" above, then type this: select within (6.0, 377:A); cpk only; display selected; center selected; zoom 1000; select 377:A; color white


Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Guo R, Zong S, Wu M, Gu J, Yang M.
Cell. 2017 Sep 7;170(6):1247-1257.e12. doi: 10.1016/j.cell.2017.07.050.(PubMed)

pdb ID (5xtd)