Conservation in subunit FS1 Back
Human Complex I is shown with each of the 45 subunits colored a different color. The prosthetic groups, including FMN, FeS clusters, quinone, NADP+ and lipids are shown in space filling, colored by cpk.

Subunit FS1 is colored according to conservation. Magenta is most conserved, cyan is least conserved.

Isolated view of subunit FS1.

I177 in FS1    Undo
E211 in FS1    Undo
R241 in FS1    Undo
R386 in FV1    Undo
Atoms within 6 Å of subunit FS1 are shown in cpk according to the coloring scheme:
                                               
 FV1  nuoF  :A
 FV2  nuoE  :O
 FV3    :K
 FS2  nuoD  :Q
 FS3  nuoC  :P
 FS4    :L
 FS6      :T
 FS8    nuoI  :B
 FA2    :F
 FA6    :E
 FA7    :I
 FA9    :J
 FA12    :N
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Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Guo R, Zong S, Wu M, Gu J, Yang M.
Cell. 2017 Sep 7;170(6):1247-1257.e12. doi: 10.1016/j.cell.2017.07.050.(PubMed)

pdb ID (5xtd)