|Conservation in subunit FV1 (nuoF)||Back to subunit list|
Human Complex I is shown with each of the 45 subunits colored a different color. The prosthetic groups, including FMN, FeS clusters, quinone, NADP+ and lipids are shown in space filling, colored by cpk.
Subunit FV1 is colored according to conservation. Magenta is most conserved, cyan is least conserved.
Isolated view of subunit FV1.
R128 in FV1 Undo (R102)Atoms within 6 Å of subunit FV1 are shown in cpk according to the coloring scheme:
Spin on Spin off
Protein wireframe Protein cpk
Zoom 400 Zoom 600 Zoom 800
Atoms within 8 Å of E377 are shown. E377 of NDUFV1 and Arg200 of NDUFS1 (nuoG) and one FeS cluster are shown in CPK
Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Guo R, Zong S, Wu M, Gu J, Yang M.
Cell. 2017 Sep 7;170(6):1247-1257.e12. doi: 10.1016/j.cell.2017.07.050.(PubMed)
pdb ID (5xtd)