Conservation in subunit ND4 Back              nuoM
Human Complex I is shown with each of the 45 subunits colored a different color. The prosthetic groups, including FMN, FeS clusters, quinone, NADP+ and lipids are shown in space filling, colored by cpk.

Subunit ND4 is colored according to conservation. Magenta is most conserved, cyan is least conserved.

Isolated view of subunit ND4.

L158 in ND4    Undo     (L183)
I165 in ND4    Undo     (L190)

Atoms within 6 Å of subunit ND4 are shown in cpk according to the coloring scheme:
 ND5  nuoL  :l
 ND2  nuoN  :i
 FS2  nuoD  :Q
 FB6    :b
 FB4    :o
 FB10    :d
 FB9    :p
 FB8      :c
 FB5    :a
 FA10    :w
 FA11    :V
 FA8    :u
 FB1    :n
 FC2    :g
 FB11    :e
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Protein wireframe   Protein cpk
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Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Guo R, Zong S, Wu M, Gu J, Yang M.
Cell. 2017 Sep 7;170(6):1247-1257.e12. doi: 10.1016/j.cell.2017.07.050.(PubMed)

pdb ID (5xtd)