Peer-Reviewed Journals
- Chemical and structural analysis of a photoactive vertebrate cryptochrome from pigeon.
Zoltowski, B. D..; Chelliah, Y.; Wickramaratne, A.; Jarocha, L.; Karki, N.; Xu, W.; Mouritsen, M.; Hore, P. J.; Hibbs, R. E.; Green, G. B.; Takahashi, J. S.; PNAS 2019, 116(39), 19449-19457.
- Allosteric Mechanism of the circadian protein Vivid resolved through Markov state model and machine learning analysis.
Zhou, H.; Dong, D.; Verkhivker, G.; Zoltowski, B. D.; Tao, P. PLOS Comp Biol 2019
- Characterization of a Vivid Homolog in Botrytis cinerea.
Foley, B. J.; Stutts, H.; Schmitt, S. L.; Lokhandwala, J.; Nagar, A.; Zoltowski, B. D. Photochemistry and Photobiology 2018, 94(5), 985-993.
- Revealing Hidden Conformational Space of LOV Protein VIVID Through Rigid Residue Scan Simulations Zhou, H.; Zoltowski, B. D.; Tao, P. Scientific Reports 2017, 426626
- Kinetics of the LOV domain of Zeitlupe determine its circadian function in Arabidopsis
Pudasaini, A.; Shim J. S.; Song, Y. H.; Shi, H.; Kiba, T.; Somers, D. E.; Imaizumi, T.; Zoltowski, B. D. Elife 2017, 6, e21646.
- Optimized second-generation CRY2-CIB dimerizers and photoactivatable Cre recombinase.
Taslimi, A.; Zoltowski, B. D.; Miranda, J. G.; Pathak, G. P.; Hughes, R. M.; Tucker, C. L. Nat Chem Biol 2016, 12(6), 425-30.
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A Native Threonine Coordinates Ordered Water to Tune Light-Oxygen-Voltage (LOV) Domain Photocycle Kinetics and Osmotic Stress Signaling in Trichoderma reesei ENVOY.
Lokhandwala, J.; Silverman, Y. d. I. V. R. I.; Hopkins, H. C.; Britton, C. W.; Rodriguez-Iglesias, A.; Bogomolni, R.; Schmoll, M.; Zoltowski, B. D. J Biol Chem 2016, 291(28), 14839-50.
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Resolving cryptic aspects of cryptochrome signaling.
Zoltowski, B. D. Proc Natl Acad Sci U.S.A. 2015, 112 (29), 8811-2.
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LOV-based optogenetic devices: light-driven modules to impart photoregulated control of cellular signaling.
Pudasaini, A.; El-Arab, K. K.; Zoltowski, B. D. Front Mol Biosci 2015, 2, 18.
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Structural biochemistry of a fungal LOV domain photoreceptor reveals an evolutionarily conserved pathway integrating light and oxidative stress.
Lokhandwala, J.; Hopkins, H. C.; Rodriguez-Iglesias, A.; Dattenbock, C.; Schmoll, M.; Zoltowski, B. D. Structure 2015, 23(1), 116-25.
- El-Arab, K. K.; Pudasaini, A.; Zoltowski, B. D.
Short LOV Proteins in Methylocystis Reveal Insight into LOV Domain Photocycle Mechanisms. PLoS One 2015, 10(5), e0124874. [ Link ]
- Zoltowski, B. D.; Imaizumi, T.
Structure and Function of the ZTL/FKF1/LKP2 Group Proteins in Arabidopsis. Enzymes 2014, 35, 213-39. [ Link ]
- Zoltowski, B. D.; Motta-Mena, L. B.; Gardner, K. H.
Blue light-induced dimerization of a bacterial LOV-HTH DNA-binding protein. Biochemistry 2013, 52(38), 6653-61. [ Link ]
- Pudasaini, A.; Zoltowski, B. D.
Zeitlupe senses blue-light fluence to mediate circadian timing in Arabidopsis thaliana. Biochemistry 2013, 52(40), 7150-8. [ Link ]
- Levy, C.; Zoltowski, B. D.; Jones, A. R.; Vaidya, A. T.; Top, D.; Widom, J.; Young, M. W.; Scrutton, N. S.; Crane, B. R.; Leys, D.
Updated structure of Drosophila cryptochrome. Nature 2013, 495(7441), E3-4. [ Link]
- Gardner, K. H.; Motta-Mena, L. B.; Zoltowski, B. D.
Biophysical Studies of Natural Photoreceptors: Application to Optogenetic Tool Optimization.Biophys J 2012, 102(3), 40a-41a. [ Link ]
- Zoltowski, B. D.; Vaidya, A. T.; Top, D.; Widom, J.; Young, M. W.; Crane, B. R.
Structure of full-length Drosophila cryptochrome. Nature 2011, 480(7377), 396-9. [ Link ]
- Zoltowski, B. D.; Nash, A. I.; Gardner, K. H.
Variations in protein-flavin hydrogen bonding in a light, oxygen, voltage domain produce non-Arrhenius kinetics of adduct decay. Biochemistry 2011, 50(41), 8771-9. [ Link ]
- Zoltowski, B. D.; Gardner, K. H.
Tripping the light fantastic: blue-light photoreceptors as examples of environmentally modulated protein-protein interactions. Biochemistry 2011, 50(1), 4-16. [ Link ]
- Zoltowski, B. D.; Vaccaro, B.; Crane, B. R.
Mechanism-based tuning of a LOV domain photoreceptor. Nat Chem Biol 2009, 5(11), 827-34. [ Link ]
- Lamb, J. S.; Zoltowski, B. D.; Pabit, S. A.; Li, L.; Crane, B. R.; Pollack, L.
Illuminating Solution Responses of a LOV domain protein with photocoupled small-angle X-ray scattering. J Mol Biol 2009, 393(4), 909-19. [ Link ]
- Zoltowski, B. D.; Crane, B. R.
Light activation of the LOV protein vivid generates a rapidly exchanging dimer. Biochemistry 2008, 47(27), 7012-9. [ Link ]
- Lamb, J. S.; Zoltowski, B. D.; Pabit, S. A.; Crane, B. R.; Pollack, L.
Time-resolved dimerization of a PAS-LOV protein measured with photocoupled small angle X-ray scattering. J Am Chem Soc 2008, 130(37), 12226-7. [ Link ]
- Bessonov, N.; Pojman, J.; Viner, G.; Volpert, V.; Zoltowski, B. D.
Instabilities of diffuse interfaces. Math Model Nat Pheno 2008, 3(1), 108-125. [ Link ]
- Zoltowski, B. D.; Schwerdtgefer, C.; Widom, J.; Loros, J. J.; Bilwes, A. M.; Dunlap, J. C.; Crane, B. R.
Conformational switching in the fungal light sensor Vivid. Science 2007, 316(5827), 1054-7. [ Link ]
- Zoltowski, B. D.; Chekanov, Y.; Masere, J.; Pojman, J. A.; Volpert, V.
Evidence for the existence of an effective interfacial tension between miscible fluids. 2. Dodecyl acrylate-poly(dodecyl acrylate) in a spinning drop tensiometer. Langmuir 2007, 23(10), 5522-31. [ Link ]
- Zoltowski, B. D.; Leard, K.; Carter, N.; Budzinski, K.; Ainsworth, W.; Pojman, J. A.
The role of gravity in the motion of plasma arcs inside ‘Plasma Balls’: An investigation in the NASA reduced gravity student flight opportunities program. Microgravity Sci Technol 2006, 18(2), 39-43. [ Link ]
- Pojman, J. A.; Whitmore, C.; Turco Liveri, M. L.; Lombardo, R.; Marszalek, J.; Parker, R.; Zoltowski, B. D.
Evidence for the existence of an effective interfacial tension between miscible fluids: isobutyric acid-water and 1-butanol-water in a spinning-drop tensiometer. Langmuir 2006, 22(6), 2569-77. [ Link ]
- Bessonov, N.; Volpert, V. A.; Pojman, J. A.; Zoltowski, B. D.
Numerical simulations of convection induced by Korteweg stresses in miscible polymermonomer systems. Microgravity Sci Technol 2005, 17(1), 8-12. [ Link ]
- Antrim, D.; Bunton, P.; Lewis, L. L.; Zoltowski, B. D.; Pojman, J. A.
Measuring the mutual diffusion coefficient for dodecyl acrylate in low molecular weight poly(dodecyl acrylate) with laser line deflection (Wiener’s Method) and the fluorescence of pyrene. J Phys Chem B 2005, 109(23), 11842-9. [ Link ]
Patents
- Gardner, Kevin H., Motta-Mena, Laura B., Zoltowski, Brian D. “Blue-Light Inducible System for Gene Expression.” Publication number WO2013074911 A1 (Publication Date: May 23rd, 2013)
Seminars
- Zoltowski, B.D., “Computational and structural studies of LOV domain photoreceptors reveals evolutionary selection of a divergent signaling pathway” 2019 ESP-IUPB World Congress, August 29th, 2019.
- Zoltowski, B.D., “Chemical Integration of Circadian and Photoperiodic Clocks in Plants” Society for Research on Biological Rhythms, Amelia Island Florida, May 13th 2018.
- Zoltowski, B.D., “Blue Light Signaling by Flavin-binding Photoreceptors” Gordon Research Conference: Photosensory Receptors and Signal Transduction, Discussion Leader, March 8th, 2018.
- Zoltowski, B.D., “Chemical Integration of Circadian and Photoperiodic Clocks in Plants” Department of Chemistry and Biochemistry, UC-Santa Cruz, November 27th 2017.
- Zoltowski, B.D., “Establishing an independent research lab” Keynote lecture, UT-Southwestern Postdoctoral Association Annual Retreat, Dallas, TX, September 22nd 2017.
- Zoltowski, B.D., “Chemical Integration of Circadian and Photoperiodic Clocks in Plants” American Mathematical Society, University of North Texas, September 9th 2017.
- Zoltowski, B.D., “Chemical Integration of Circadian and Photoperiodic Clocks in Plants” CHESS, Cornell University, June 7th 2017.
- Zoltowski, B.D., “Chemical Integration of Circadian and Photoperiodic Clocks in Plants” Department of Chemistry and Biochemistry, UT-Dallas, November 4th 2016.
- Zoltowski, B.D., “Chemical Integration of Circadian and Photoperiodic Clocks in Plants” Department of Biology, Trinity University, September 19th 2016.
- Zoltowski, B.D., “Chemical Integration of Circadian and Photoperiodic Clocks in Plants” Department of Chemistry and Biochemistry, University of Southern Mississippi, September 9th 2016.
- Zoltowski, B.D., “Chemical Integration of Circadian and Photoperiodic Clocks in Plants” Society for Research on Biological Rhythms (SRBR), Palm Harbor, FL, May 25th, 2016.
- Zoltowski, B.D., “Chemical Integration of Circadian and Photoperiodic Clocks in Plants” SMU, Math-Bio Seminar Series, April 4th 2016.
- Zoltowski, B.D., “Chemical Integration of Circadian and Photoperiodic Clocks in Plants” Texas A&M University, Texas Society for Circadian Biology and Medicine, April 2nd 2016.
- Zoltowski, B.D., "Integrating Stress Response Pathways with a Little LOV" Gordon Research Conference: Photosensory Receptors and Signal Transduction, January 26th, 2016.
- Zoltowski, B.D., “Linking Fundamental Chemistry to Organism Physiology: Tuning circadian and photoperiodic clocks in plants.” University of California-Davis, November, 13th, 2015.
- Zoltowski, B.D., “Linking Fundamental Chemistry to Organism Physiology: Tuning circadian and photoperiodic clocks in plants.” University of Texas-El Paso, October, 23rd, 2015.
- Zoltowski, B.D., “Linking Fundamental Chemistry to Organism Physiology: Tuning circadian and photoperiodic clocks in plants.” Dartmouth College, September, 22nd, 2015.
- Zoltowski, B.D., “Photochemical Regulation of Circadian Clock Function,” International Symposium on Plant Photobiology, University of Texas-Austin, May 28, 2015.
- Zoltowski, B.D., "Allostery and the clock: Engineering Photoreceptors to Manipulate Circadian Clocks and Optogenetic Tools,” Laura Sheard Lecture, University of Washington, Department of Pharmacology, May 12th 2015.
- Zoltowski, B.D., “Integration of light and oxidative stress in diverse organisms” Southwest Regional Meeting of the American Chemical Society, Ft. Worth, TX, November 21st 2014.
- Zoltowski, B.D., “Improving Optogenetic Devices: Using Chemistry and Structural Mechanisms to Provide Tunable Platforms for Light-Controlled Protein:Protein Interactions” XXXVII Reunión Anual de la Sociedad de Bioquímica y Biología Molecular de Chile, Puerto Varas Chile, October 1st 2014.
- Zoltowski, B.D., “Improving Optogenetic Devices: Using Chemistry and Structural Mechanisms to Provide Tunable Platforms for Light-Controlled Protein:Protein Interactions” Synthetic Biology Workshop, Pontificia Universidad Católica de Chile, Santiago, Chile, September 29th 2014.
- Zoltowski, B.D., “Divergent Structural Mechanisms of Circadian Photoreception in Filamentous Fungi” University of Texas Health Science Center, SECTS for CLOCKs, March 22nd 2014.
- Zoltowski, B.D., “Chemistry of the Clock” DFW American Chemical Society, Young Investigators Symposium, January 25th 2014.
- Zoltowski, B.D., "Mathematical Models of the Circadian Clock," Southern Methodist University, Math-Biology Research Cluster, December 9th, 2013.
- Zoltowski, B.D.,“Chemistry of Circadian and Photoperiodic Clocks,” Texas Christian University, Department of Chemistry, September 26, 2013.
- Zoltowski, B.D.,“Oxidative Stress and Circadian Photoreception,” Texas A&M University, SECTS for CLOCKs, Health Science Center, April 23, 2013.
- Pudasaini, A., Zoltowski, B.D., "Photochemical Characterization of Arabidopsis Zeitlupe", 46th ACS DFW Meeting-in-Miniature, Commerce, TX, April 27, 2013.
- Hopkins, H., Zoltowski, B.D., “Tuning of Reaction Mechanisms of Circadian Clock Photoreceptors,” University of Texas-Arlington, Department of Chemistry, April 5th, 2013.
- Zoltowski, B.D.,“Structure and Function of Circadian Clock Photoreceptors,” Texas Womens University, Department of Biology, November 2nd 2012.
- Zoltowski, B.D.,“Biophysical Methods for the Elucidation of Biological Mechanisms,” University of South Bohemia, Czeske Budejovice, Czech Republic, March 20th 2012.
- Zoltowski, B.D.,“Structure and Function of Circadian Clock Photoreceptors,” Czech Academy of Sciences, Czeske Budejovice, Czech Republic, March 18th 2012.
- Zoltowski, B.D.,“Structure and Function of Drosophila Cryptochrome,” Howard Hughes Medical Institute; Janelia Farms, March 6th 2012.
- Zoltowski, B.D.,“The Chemistry and Biology of the Clock” Southern Methodist University, Department of Biology, September 12th 2011.
- Zoltowski, B.D.,“Structure and Proposed Mechanism of Drosophila Cryptochrome” Southern Methodist University, Department of Biology, April 15th 2011.
- Zoltowski, B.D., Nash, Abigail, Gardner, Kevin H.,“Biophysical Studies of a LOV-HTH DNA Binding Protein” Gordon Research Conference, Barga Italy, April 22nd 2010.
- Zoltowski, B.D., Nash, Abigail, Gardner, Kevin H., “Biophysical Studies of a LOV-HTH DNA Binding Protein” Gordon Research Seminar, Barga, Italy, April 17th 2010.
- Zoltowski, B.D.,“Vivid: Photo-induced Transient Dimerization” Wentink Symposium, Ithaca, NY, April 22nd 2008.
- Zoltowski, B.D., Pojman, John A.“Using Spinning Drop Tensiometry to Determine the Square Gradient Parameter for Dodecyl Acrylate/Poly (Dodecyl Acrylate) for Use in the TIPMPS Flight Investigation" Microgravity Science and Space Processing, 41th AIAA Aerospace Sciences National Meeting and Exhibit, Reno, NV, 6-9 January 2003.
- Zoltowski, B.D., Bessonov, Nick, Volpert, Vitaly, Pojman, John A., “Numerical Simulations of Transient Interfacial Phenomena in Miscible Polymer Systems,” 41th AIAA Aerospace Sciences National Meeting and Exhibit, Reno, NV, 6-9 January 2003.
- Zoltowski, B.D., Budzinski, Kristi, Carter, Nicholas, Leard, Kayce, Watters, Christina, Pojman, John A. “Down to Earth” Microgravity Experiments: Classroom Demonstrations of Microgravity Research,” 40th AIAA Aerospace Sciences Meeting and Exhibit, Reno, NV, 14-17 January 2002.
Posters
- Ashutosh Pudasaini, Brian D Zoltowski, "Chemical and structural mechanisms of circadian clock protein Zeitlupe"; Photosensory Receptors & Signal Transduction, Gordon Research Conference (GRC), 6-11 April 2014, Lucca (Barga) Italy, P35.
- Ashutosh Pudasaini, Brian D Zoltowski, "Chemical and structural mechanisms of circadian clock protein Zeitlupe"; Photosensory Receptors & Signal Transduction, Gordon Research Seminars (GRS), 4-5 April 2014, Lucca (Barga) Italy, P28.
- Hilary Hopkins, Jameela Lokhandwala, Brian D. Zoltowski, "Divergent Structural Mechanisms of Blue-Light Photoreception in the Filamentous Fungi Trichoderma Reesei"; Photosensory Receptors & Signal Transduction, Gordon Research Seminars (GRS), 4-5 April 2014, Lucca (Barga) Italy.
- Hilary Hopkins, Jameela Lokhandwala, Brian D. Zoltowski, "Divergent Structural Mechanisms of Blue-Light Photoreception in the Filamentous Fungi Trichoderma Reesei"; Photosensory Receptors & Signal Transduction, Gordon Research Conference (GRC), 6-11 April 2014, Lucca (Barga) Italy.
- Kaley El-Arab, Abby Slyman, Ashutosh Pudasaini, Brian D Zoltowski, "Chemical Characterization of Novel Bacterial LOV-domain Photoreceptors"; Current Topics in Biological Chemistry, 247th ACS National Meeting & Exposition, 18 March 2014, Dallas, Texas, BIOL-239.
- Hilary Hopkins, Jameela Lokhandwala, Brian D. Zoltowski, "Divergent Structural Mechanisms of Blue-Light Photoreception in the Filamentous Fungi Trichoderma Reesei"; Current Topics in Biological Chemistry, 247th ACS National Meeting & Exposition, Dallas, Texas, March 18, 2014.
- Ashutosh Pudasaini, Brian D Zoltowski, "Blue light photoreceptor Zeitlupe senses light fluence to regulate plant circadian clock"; Current Topics in Biological Chemistry, 247th ACS National Meeting & Exposition, March 18, 2014, Dallas, Texas.
- Kaley El-Arab, Katie Powers, Ashutosh Pudasaini, Brian D. Zoltowski, "Photochemical Characterization of LOV Domain Containing Photoreceptors"; 69th Southwest Regional Meeting of ACS, Waco, Texas, November 16-19, 2013.
- Pudasiaini, A., Zoltowski, B.D., "Photochemical Characterization of Arabidopsis Zeitlupe"; Chronobiology Gordon Research Conference, Salve Regina University, Newport, Rhode Island, July 14-19, 2013.
- Pudasiaini, A., Zoltowski, B.D., "Photochemical Characterization of Arabidopsis Zeitlupe"; International Symposium on Plant Photobiology (ISPP), University of Edingburgh, Edinburgh, Scotland, June 5-9, 2013.
- Pudasiaini, A.; Zoltowski, B.D., "Photochemical Characterization of Arabidopsis Zeitlupe" Southern Methodist University Research Day, Dallas, Texas, February 27, 2013.