FB3 in Human Complex I

Conservation in subunit FB3

Human Complex I is shown with each of the 45 subunits colored a different color. The prosthetic groups, including FMN, FeS clusters, quinone, NADP+ and lipids are shown in space filling, colored by cpk.

Subunit FB3 is colored according to conservation. Magenta is most conserved, cyan is least conserved.

Isolated view of subunit FB3. (chain Z)

W22 in FB3 Undo

Atoms within 6 Å of subunit FB3 are shown in cpk according to the coloring scheme:

ND5 nuoL :l

FAB1 :X

FB2 :Y

FB5 :a

FB9 :p

Spin on   Spin off   Rotate 180
Protein wireframe   Protein cpk
Protein cartoon   Colored by sec. structure
Rainbow color: N-term-blue, C-term-red
Zoom 200   Zoom 400   Zoom 600

Architecture of Human Mitochondrial Respiratory Megacomplex I₂III₂IV₂.
Guo R, Zong S, Wu M, Gu J, Yang M.
Cell. 2017 Sep 7;170(6):1247-1257.e12. doi: 10.1016/j.cell.2017.07.050.(PubMed)

pdb ID (5xtd)