Conservation in subunit FS2 (nuoD) Back to subunit list
Human Complex I is shown with each of the 45 subunits colored a different color. The prosthetic groups, including FMN, FeS clusters, quinone, NADP+ and lipids are shown in space filling, colored by cpk.

Subunit FS2 is colored according to conservation. Magenta is most conserved, cyan is least conserved.

Isolated view of subunit FS2.

R138 in FS2    Undo    (R274)
Y141 in FS2    Undo     (Y277)
R228 in FS2    Undo    (R364)
Atoms within 6 Å of subunit FS2 are shown in cpk according to the coloring scheme:
 FS1  nuoG  :M
 FS3  nuoC  :P
 FS4    :L
 FS6      :T
 FS7    :C
 FS8  nuoI  :B
 FA5    :H
 FA6    :E
 FA7    :I
 FA10    :w
 FA11    :V
 FA12    :N
 FA13    :W
 FB11    :e
 ND1  nuoH  :s
 ND2  nuoN  :i
 ND3  nuoA  :j
 ND4  nuoM  :r
 ND5  nuoL  :l
 ND4L  nuoK  :k
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Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Guo R, Zong S, Wu M, Gu J, Yang M.
Cell. 2017 Sep 7;170(6):1247-1257.e12. doi: 10.1016/j.cell.2017.07.050.(PubMed)

pdb ID (5xtd)