Conservation in subunit FS8 (nuoI) Back to subunit list
Human Complex I is shown with each of the 45 subunits colored a different color. The prosthetic groups, including FMN, FeS clusters, quinone, NADP+ and lipids are shown in space filling, colored by cpk.

Subunit FS8 is colored according to conservation. Magenta is most conserved, cyan is least conserved.

Isolated view of subunit FS8. (chain B)

E63 in FS8    Undo    (E5)
P85 in FS8    Undo     (P34)
R138 in FS8    Undo    (R86)
A159 in FS8    Undo     (A108)
Atoms within 6 Å of subunit FS8 are shown in cpk according to the coloring scheme:
 FS1  nuoG  :M
 FS2  nuoD  :Q
 FS3  nuoC  :P
 FS4    :L
 FS6      :T
 FS7    :C
 FA1    :S
 FA3    :U
 FA5    :H
 FA7    :I
 FA9    :J
 FA12    :N
 FA13    :W
 ND1  nuoH  :s
Spin on   Spin off   Rotate 180
Protein wireframe   Protein cpk
Protein cartoon   Colored by sec. structure
Rainbow color: N-term-blue, C-term-red
Zoom 200   Zoom 400   Zoom 600

Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Guo R, Zong S, Wu M, Gu J, Yang M.
Cell. 2017 Sep 7;170(6):1247-1257.e12. doi: 10.1016/j.cell.2017.07.050.(PubMed)

pdb ID (5xtd)