FV2 in Human Complex I

Conservation in subunit FV2 (nuoE)

Human Complex I is shown with each of the 45 subunits colored a different color. The prosthetic groups, including FMN, FeS clusters, quinone, NADP+ and lipids are shown in space filling, colored by cpk.

Subunit FV2 is colored according to conservation. Magenta is most conserved, cyan is least conserved.

Isolated view of subunit FV2.

R128 in FV2    Undo (R102)
R199 in FV2    Undo (T173)
E377 in FV2    Undo (E349)
R386 in FV2    Undo (R358)

Atoms within 6 Å of subunit FV2 are shown in cpk according to the coloring scheme:

FV1 nuoF :A

FV3 :K

FS1 nuoG :M

FS4 :L

FS6 :T

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Architecture of Human Mitochondrial Respiratory Megacomplex I₂III₂IV₂.
Guo R, Zong S, Wu M, Gu J, Yang M.
Cell. 2017 Sep 7;170(6):1247-1257.e12. doi: 10.1016/j.cell.2017.07.050.(PubMed)

pdb ID (5xtd)