Complex I is the
first and largest enzyme of the respiratory chain, coupling electron
transfer between NADH and
ubiquinone to the translocation of four protons across the membrane. It
has a central role in cellular energy
production and has been implicated in many human neurodegenerative
diseases.
| The overview
of Complex I |
Page 1 |
| Fold of
antiporter-like subunits |
Page 2 |
| Ligands in ComplexI | Page 3 |
| Interactions between subunits | Page 4 |
| Mutation in
Complex I |
Page 5 |