An Interactive Jmol Tutorial about Some Protein

Hadeel Bamershed.2016

p53 Tumor Suppressor

p53 tumor suppressor protects the body from DNA damage and cancer.
p53 tumor supressor. Flexible portions of the molecule that are not included in the structures are shown schematically.

Figure: shows the 2-dimensional structure of the p-53 protein with the vertical lines showing the points of mutation (Joerger & Fersht, 2010).

The structure of p53
Page 1
Fold of p53
Page 2
Mutation in human & mouse Page 3
Sites of mutation of p53 Page 4
The role of p53 Page 5
Inhibition of p53 Page 6
Activation of p53 Page 7
Therapy of p53
Page 8